Methadone

Abstract Importance In 2023, more than 80 000 individuals died from an overdose involving opioids. With almost two-thirds of the US jail population experiencing a substance use disorder, jails present a key opportunity for providing...

Abstract Objective Methadone coverage is poor in many countries due in part to methadone induction being possible only in specialized care (SC). This multicenter pragmatic trial compared the effectiveness of methadone treatment between two...

Background: Physical health problems are common in people receiving opioid agonist treatment (OAT). A study was conducted on these health issues in OAT patients in the Czech Republic and Norway from 2010 to 2019, with a focus on gender...

Opioid dependence is associated with substantial health and social burdens, and opioid agonist treatment (OAT) is highly effective in improving multiple outcomes for people who receive this treatment. Methadone and buprenorphine are common...

Abstract Aim To investigate the real-world effectiveness of pharmacological treatments (buprenorphine, methadone) of opioid use disorder (OUD). Design A nation-wide, register-based cohort study. Setting Sweden. Participants All residents...

Abstract Background Epidemiological data from Mexico have documented an increase in heroin use in the last decade. However, there is no comprehensive care strategy for heroin users, especially those who have been accused of a crime. The...

Abstract Background Medication treatment for opioid use disorder (OUD) (MOUD; buprenorphine and methadone) reduces opioid use and overdose. Discontinuation of MOUD can quickly lead to relapse, overdose and death. Few persons who initiate...

Cannabis is the most widely used illegal substance in the world, with a global prevalence of 4% among people aged 15 to 64 years and a recent trend of growing use. Cannabis usage can have negative health consequences, such as impaired...

Abstract Background Cannabis use during methadone treatment may negatively impact treatment outcomes. The aim of this study was to determine the prevalence and pattern of cannabis use among patients attending a methadone treatment clinic in...