ABSTRACT Introduction and Aims: Transfer from methadone to buprenorphine is problematic for many opioid-dependent patients, with limited documented evidence or practical clinical guidance, particularly for the range of methadonedoses...
Abstract Background Mexico recently enacted drug policy reform to decriminalize possession of small amounts of illicit drugs and mandated that police refer identified substance users to drug treatment. However, the economic implications of...
Seminal work from Australia identified these as the three pillars of medication-based treatment of drug dependence; they form the kernel of this bite’s exploration of organisational influences on these treatments. Ethos, dose, and...
Highlights MMT during incarceration leads to lower injection drug and heroin use. MMT during incarceration leads to fewer non-fatal overdoses. MMT during incarceration leads to higher rates of engagement in treatment. Abstract Recently...
Effectiveness Bank Analysis: Keep Maintaining Opiate-Dependent Prisoners From the USA, a rare randomised trial found in favour of continuing methadone maintenance when patients entered prison rather than compulsory withdrawal. The potential...
Abstract Methadone is used for medication-assisted treatment of heroin addiction during pregnancy. The neurodevelopmental outcome of children with prenatal methadone exposure can be sub-optimal. We tested the hypothesis that brain...
Introduction: Both heroin use and depression are significant health problems. Methadone maintenance treatment (MMT) can be of great benefit to heroin users. However, changes in the level of depression in heroin users during MMT are not...
Summary What is already known about this topic? Opioid overdose deaths in the United States have been increasing since 1999, initially driven by prescription opioid misuse and more recently by heroin and other illicit opioid use. What is...