In a recent article, Gunawan and colleagues explore how the Incentive Salience (IS) domain in the Addictions Neuroclinical Assessment (ANA) framework relates to alcohol motivation and alcohol insensitivity. Their findings support previous research suggesting a connection between alcohol insensitivity and the motivation-driven response to alcohol-related cues. This review highlights the importance of understanding how individuals with low alcohol sensitivity (LS) experience stronger reactions to alcohol cues compared to those with high alcohol sensitivity (HS). It also emphasizes the need for...